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Why the hype around the drug Wegovy and Ozempic (semaglutide)?
The drug Semaglutide ( Wegovy ) for diabetes has been O.K. by the FDA for weight loss in teenagers and for treating obesity in children . This is good news for parents and wellness care providers , which was release after a study discovered the system of weights loss drug can help the teems in substantially decreasing the BMI . This drug acts by suppressing the appetite , which leads to minify intake of calories and results in weight going .
Treating Teenage Obesity with Semaglutide
The U.S. Food and Drug Administration has give the green signal to the diabetes medicine for treating corpulency in adolescents.(1)A survey discover that the type 2 diabetes drug semaglutide is equally effective in obese stripling as it is in weighty adults . This drug is administered via injection once a workweek and the brand figure of this are the famed Ozempic and Wegovy . Wegovy has been approved in treating fry as young as 12 .
The FDA has given its approval after a major study discovered the benefits of this drug in stripling .
The cogitation published in The New England Journal of Medicine in December let out that overweight or obese teenagers who took this drug and also followed modus vivendi modifications had about 16 % reduction in body mass index finger ( BMI ) in around 68 week . Wegovy also head to advance in various cardiometabolic health egress . It is clock time for parents and doctors to rejoice .
What is Semaglutide?
Semaglutide is a glucagon - like peptide-1 analogue and is properly now only approve for usance in adults tolerate from obesity or health conditions related to obesity.(2 , 4)This drug acts by inhibit the appetite , which in turn decreases the calorie intake and make weight going .
According to the inquiry , the recent finding throw a ignitor on new bright treatment option for obese adolescents , peculiarly at a time where childhood obesity rates are increasing.(3)It was discovered that Semaglutide worked much well than other drugs for weight loss . It the study , the effectualness of semaglutide was compared to a placebo in 201 teenager having obesity between the eld of 12 and 17 . In this study about 134 of the participant were make 2.4 milligram of semaglutide via the hypodermic path once a week and adhered to life style interventions for 68 weeks . Among the total participants , 67 received a placebo and adhered to modus vivendi intercession for 68 weeks .
After the continuance of treatment , the expert track the wellness of the participant for extra seven weeks and it was discovered that participants who have semaglutide had about 16.1 % step-down in BMI when compare to their previous baseline BMI . The participant who were given the placebo had very soft increase in BMI . Other than this , about 73 % of participant who were given semaglutide lost a lower limit of 5 % of their consistency weight when equate to 18 % of the participants who ask the placebo .
There were also see improvements in unlike cardiometabolic risk constituent , including cholesterol , lipoid , triglycerides , glycated haemoglobin levels and shank circumference . Participants who took semaglutide also had weight loss along with unspoilt timbre of life . According to the experts , the benefits of semaglutide were importantly greater when compare to other weight - red ink drugs that were sanction for teenagers with obesity .
What are the Side Effects of Semaglutide in Teens?
Just like grownup , the common contrary effects of semaglutide in teens were gastrointestinal problems ; however , the symptom were curtly - lived and mild .
What is the Current Treatment for Childhood Obesity?
The present guidelines for small fry with corpulency is adopting various lifestyle intervention ; however , research has found that it becomes very difficult to get long - term weight loss outcome with only lifestyle changes after the obesity has developed . If young citizenry are not able to achieve their goals of weight loss by lifestyle interventions , then help is there for them in the mannikin of pharmaceutic medicine with albeit special options .
The American FDA had already approved three weight loss drug for adolescent with obesity lie of orlistat , liraglutide and phentermine - topiramate .
What is the Opinion of Pediatricians of Semaglutide?
They say that the consequence are prognosticate ; however , they should be cautiously render as the subject area was not done in an ethnically diverse population and the drug was also not completely tested in teenagers with character 2 diabetes . More studies are needed in groups also , but there is Leslie Townes Hope for adolescent who are obese and are struggling with weight loss . This news program has put everyone one step nigher to addressing the epidemic of corpulency . However , like refer before there are more discipline need to well understand the side effects and the effectiveness of the drug in various ethnic groups . Further studies will allow one to sympathise this drug more and create better conceptualisation of next - propagation medications .
A type-2 diabetes drug was approved by the FDA for cover obesity in adolescents as unseasoned as the age 12.(5)This news was revealed a calendar week after a recent study discovered that semaglutide , a case 2 diabetes and obesity drug , is as effective in teens with corpulency as it is in adults with obesity . These new findings have thrown Light Within on promise new treatment options for teenagers suffering from obesity .
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