leukaemia is acancerof blood andbone marrow , in which there is proliferation ofwhite blood cell . haired cadre cancer of the blood is a rarified variant of leukaemia , which causes chronic , abnormal proliferation of lymphocytes ( B - cells ) . These abnormal cell have hirsute projection under a microscope , thus the name hairy cell leukemia . There are elevated levels of leukemic cells in blood and pearl bone marrow and decreased levels of white blood cell , red blood cellsand platelets . This asymmetry in blood cell remove the organic structure prone to infection , bleed disorders andanemia .
What is The Survival Rate for Hairy Cell Leukemia?
Hairy cell leukaemia has good response to treatment and there is remission of cancer with a 95 % chance of recuperation from the disease . Hairy cell leukemia has confident prognosis with an excellent survival rate . There is no lasting treatment for hirsute cell leucaemia , so it is an incurable disease . However , with chemotherapy the disease is show to undergo a 10 twelvemonth remission . Despite lacking a permanent cure , the survival pace of affected role is good and the patients continue to live a normal and goodish liveliness with long term monitoring of the disease . The data regarding long term effect of the disease is limited due to bound study for the prospicient term endurance rate of the disease .
The data is also limited as the disease is rare and the datum accumulation and studies are minimal . Promising results have been found in patient with chemotherapy related to pentostatin and there have been a mellow survival rate in these patients . Superior treatment options for optimum recollective condition survival rates are crushed due to sparse foresightful term statistics . Further studies are underway and hopefully in future there will be onward motion in treatment options for a longer survival charge per unit .
What Are The Causes And Symptoms Of Hairy Cell Leukemia?
Hairy cellular phone leukaemia is ordinarily seen in males with a male to distaff ratio of 5:1 and usually catch in adults in the age group of 40 to 70 geezerhood . The cause of hairy cubicle leukaemia is yet unknown . It is imagine to be a resultant role of aberration in DNA responsible for stalk electric cell production for lymphocytes in bone marrow . This aberration leads to yield of excessive , immature and abnormal lymphocytes in the parentage and ivory marrow . The cause of this aberration in DNA is also unknown . The progression of haired cell leukaemia is a very slow process and is often not diagnosed in the early stage of the disease and is mostly diagnosed by the bye in a routine blood trial . Some of the the great unwashed may introduce with symptoms of lethargy , fatigue , fall back fever and infections , gentle bruising , early satiety , weight loss , tenderness / enlargement of spleen ( due to compendium of leukemic cells),hepatomegaly , lymphadenopathy , curtness of breath , excessive sweating , pearl painand red spots on the pelt .
What Is The Diagnosis And Treatment For Hairy Cell Leukemia?
Hairy jail cell cancer of the blood may be diagnose either with blood test , which include complete blood numeration ( CBC ) and peripheral blood line defame orbone marrowtests let in pearl gist aspiration and os marrow biopsy . ACT scanor anultrasoundmay also be opted for to depend for sign of splenomegaly , hepatomegaly and lymphadenopathy . The diagnosis is confirmed with immunophenotyping ( flow cytometry ) to look for antigens relate to hairy cell leukaemia . Hairy cell cancer of the blood is a slow progressing cancer and may not require immediate treatment . Overall , treatment decision is based on symptomatic cytopenias , increasing splenomegaly , disease procession or other complications . In about 10 % of the patients , no discussion is require . Those who require treatment are treated with chemotherapy . Chemotherapy let in drugs such as cladribine and pentostatin intravenously . Other immunotherapeutic drugs admit interferon and rituximab . Generally , cladribine and pentostatin are the first line drug and have been shown to be really effective . Rituximab along with either cladribine or pentostatin has shown complete remittance in initial relapse cases . In multiple remissions , after all therapeutic option have exhausted , interferon - alpha and splenectomy are the last resort hotel .
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