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Malariais a vector - borne disease that is distribute by Anopheles mosquito carrying parasite Plasmodium . The parasite enters the human rake through the spittle of a mosquito , replicates in the liver and infects crimson stemma cells . The symptom of malaria are shake tingle , high fever , headache , sweating , and influenza - like symptom . Malaria is diagnosed by ancestry tests , rapid symptomatic tests , and other tryout . Malaria should be managed properly through antimalarial and antibiotic to prevent recurrences and remissions .
What is The Best Treatment for Malaria?
Malaria shows recurrences and backsliding if not treated decently . The man does not develop immunity against malarial infection . The drug resistance has become biggest hurdle for treatment of malaria in some geographical areas , especially in endemic areas . The disease has been showing constant health job despite a sight of initiation in medicines .
If a patient is treated for malaria , and the patient farewell acquire medicinal drug in the mid of treatment due to any reason , malaria returns back and he develops ohmic resistance to the premature medicines he was consuming . It becomes complicated to process in the 2d relapse . The physician has to try different antimalarial medicine for the second prison term to prevent relapse and provide effective treatment .
The choice of music depends upon the following factors-
After the evaluation of the sheath , your physician will start with supportive management and appropriate medicament to control symptom . Fluids andelectrolytesare provide as supportive therapy . Anti - seizure medicines may be need in some of the cases .
condom measures should also be adopted along with medicine to forfend absolution and transmission system of the disease by forbid mosquito bites . These are veritable use of recollective sleeve , long pants , insect repellantsand insecticide - treated bed cyberspace .
Antibiotics are yield in combination with antimalarial medicine for the therapeutic direction of severe and complicated cases , and case where there are special risks with unsophisticated malaria although no vaccine is commercially available forprevention of malaria .
The commonly used antimalarial drugs for the intervention of malaria are following-
Chloroquine - Chloroquine is most efficacious antimalarial music against P. ovale , P. vivax , P. malariae and drug raw P. falciparum .
Quinine - Quinine is favour as the 2d alternative of medicine in drug - resistant P. falciparum .
Quinidine Gluconate - It is used in combination with Achromycin , , or clindamycin for discourse of severe or complicated malaria .
Tetracycline - Tetracycline has potential antimalarial effect by impairing the offspring of apicoplast factor .
Artemether and lumefantrine ( Coartem)-It is given to treat acute , uncomplicated P. falciparum malaria .
Atovaquone - They are used in combining with chloroquine to treat simple P. falciparum malaria .
Mefloquine - Mefloquine is used for the treatment of drug - resistant malaria .
Primaquine ( sell as a generic)-It is used to operate hypnozoite stage of P. ovale and P. vivax to preclude lapse .
Clindamycin ( Cleocin)-It is prescribed in the combination of quinine or quinidine for treatment of drug - immune malaria .
Doxycycline - It is paired with quinine or quinidine to treat malaria due to P. falciparum .
Artesunate - Artemisinin - base combination therapy are the best available antimalarial medicinal drug presently . The ACTs are the combination of two active ingredients with their different chemical mechanism of action and are highly recommend by WHO . It is good effective therapy against malaria due to P. falciparum .
Conclusion
You should make out the trend of medicine as pass by your physician even if you palpate just to foreclose the return and drug underground developed due to uncompleted discussion of malaria .
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