This article on Epainassist.com has been reviewed by a medical master , as well as checked for facts , to secure the reader the best potential truth .
We follow a strict editorial insurance and we have a zero - allowance policy regarding any horizontal surface of plagiarism . Our articles are resourced from reputable online pages . This article may contains scientific references . The numbers in the parentheses ( 1 , 2 , 3 ) are clickable links to peer - reviewed scientific paper .
The feedback link “ Was this clause Helpful ” on this page can be used to report subject that is not accurate , up - to - particular date or refutable in any manner .
This article does not provide aesculapian advice .
What is Goiter?
Goiter is an elaboration of the thyroid gland and the size of goiter can vary . Causes of goiter mainly go around around the thyroid secretory organ , but also include systemic problem and certain risk agent . Symptoms of thyromegaly are mostly mutual , but may deviate from person to person , while some may not receive any symptoms at all . Some type of goitre have also been identified and diagnosis of goiter is important to plan right discussion choice .
struma can be a result of several conditions , including those related to the thyroid gland and thyroid gland hormones . It is important to understand the thyroid gland secretory organ , its hormones and its function to be able-bodied to manage goiter in a better way .
Thyroid Gland and Goiter
The thyroid gland secreter is an of import endocrine gland gland located in the lower part in the front of the neck . The main purpose of the thyroid gland gland is to give rise thyroid endocrine , which are responsible for for maintaining body temperature , metabolism and effective functioning of organic structure parts . The thyroid gland produce triiodothyronine ( T3 ) and T ( T4 ) , which are know as the thyroid gland hormones . The production of these hormones is mainly controlled by the Thyroid Stimulating Hormone ( TSH ) , which is secreted by the pituitary gland located at the base of the brain .
magnification of thyroid gland gland or goitre can hap due to various effort and can affect the body functions . Goiter can occur either due to over production of thyroid gland hormones or even due to underproduction . However , sometimes enlargement of thyroid gland secretory organ or goiter can be present with normal levels of thyroid hormones as well .
Types of Goiter
Some types of struma are
Causes of Goiter
Goiter can be a resultant role of various conditions . Some of the common cause of goiter include
Deficiency of Iodine
atomic number 53 insufficiency has been the commonest cause of goitre . Iodine is required for adequate output of thyroid hormones , which when found to be poor , can induce decreased product of thyroid hormone . This ishypothyroidism , due to reduce hormone production . The expansion of thyroid gland gland or goiter results as the gland tries to prevail more iodine to be able to produce sufficient amount of thyroid hormones .
I deficiency still remains a uncouth suit of goiter and a matter of concern in developing area . Many developed country have worked towards improving this status by adding iodine to salt and other fortified food for thought , with a view to foreclose thyromegaly .
Grave’s Disease
This is a form of thyroid job and a cause of goiter , where there is overproduction of thyroid gland hormones . This is hyperthyroidism , which too stimulate struma . In this event , the body react to the increased levels of thyroid gland hormone and assault the thyroid gland , causing it to swell , which ensue in goiter .
Thyroiditis
Thyroiditis is an inflammation of the thyroid secreter , which can have swelling of the thyroid secreter . This too pretend the normal production of thyroid hormones and is a common cause of thyromegaly .
Hashimoto’s Thyroiditis
This is an autoimmune term and another usual movement of goitre . Being autoimmune in nature , inHashimoto ’s Thyroiditis , a person ’s immune organisation assault the thyroid secretor causing destruction . This makes the gland unable to grow decent thyroid gland endocrine , which is counter reacted by increase in TSH hormone , to shake the thyroid secretory organ . This results in expansion of the thyroid gland and get struma .
Pregnancy
During pregnancy , production of a hormone called human chorionic gonadotropin ( HCG ) , can sometimes result in slight elaboration of the thyroid gland and have struma .
Thyroid Nodules
Development of a single tubercle in the thyroid gland secretor can induce goiter , in which case a lump can be noted in the enlarged thyroid gland secretory organ . Multinodular goiter is also one of the causes of thyromegaly , in which multiple nodule or ball are form in the thyroid gland gland , stimulate enlargement or goiter . The nodules in nodular goiter can be formed due to fluid filled cysts , benign growths or tumor in the thyroid gland and are the causal agent of thyromegaly .
Thyroid Cancer
While thyroid gland Cancer the Crab is regard to be rarified , it can cause goiter due to ontogeny and enlargement of the thyroid gland gland .
sure conditions are know to increase the risk of goiter in some cases . These admit people consuming less iodine or those lodge in in area known to have a shortage of iodine , aging population and women in general . People who have know in the past tense or have a family story of thyroid problems or any other autoimmune disorders are also at an increased risk of goiter . photograph to actinotherapy or certain medications may also increase the hazard of goiter . Some adult female may be at an increase jeopardy of goiter during their pregnancy or climacteric .
Symptoms of Goiter
Symptoms of struma may motley as some may feel enlargement of the thyroid secretory organ and related to symptom , while some may not feel any symptom at all . The elaboration of thyroid gland may be noticed as a extrusion in the front part of the neck . The size of the excrescence may diverge and sometimes be very minimally obtrusive .
Goiter or blown-up thyroid gland is normally painless , but sometimes , infection or inflammation can get pain in the swollen-headed region . Goiter can lead to feeling of tightness or heaviness in the throat area . Some citizenry having thyromegaly also show changes in their voice , high - pitched voice or sometimes gruffness of voice is a frequent symptom of goiter . cough may also be seen in some , as a symptom of goiter .
hypertrophied thyroid gland gland or goiter can exert insistence over the surrounding structures , which can result in some symptoms . Pressure over the windpipe can induce difficulty in respiration , while air pressure over the food pipe can cause difficultness in swallowing or painful swallowing . In hard cases , painful swallowing can sometimes result in reduce appetence .
Diagnosis of Goiter
Clinical examination and history of a somebody helps to discover potential shape come to to goiter . A detectable or palpable swelling in the front neck realm may need to be value properly . Minimally swollen thyroid gland must be examined carefully to see the possibleness of goiter .
Investigations for diagnosis of goiter usually include bloods tests or thyroid procedure tests to define the thyroid internal secretion levels . mental test to moderate T3 , T4 and TSH levels are commonly order . Thyroid function tests help to determine the functioning of the thyroid gland gland and aid in diagnosing of goiter . In addition blood tests , may be done to detect the mien of infection , inflaming or autoimmune disorders .
echography of the thyroid gland often helps to detect an enlarged thyroid gland and diagnose thyromegaly . It also helps to understand the character of struma and help to reveal the nature of nodules in case of nodular goiter . Radioactive thyroid scan may be considered in some showcase to diagnose struma , if relevant causes are suspect .
tissue paper biopsy may be considered in some event , particularly in nodulated struma , during which a small piece of tissue paper is taken from the enlarged thyroid . This is studied for the nature of cells present , which can help to diagnose goiter and find the exact movement of thyromegaly , base on which treatment can be project .
Scans likeCT scan , MRImay be advised to determine any abnormality in the thyroid gland or to govern out other medical conditions .
Treatment of Goiter
Treatment of goiter mainly count on the crusade , which varies from person to someone . If thyromegaly is a result of some implicit in medical shape , it is important to treat that condition first . For small goiter , which does not produce any symptoms or is harmless , no medication may be given . However , regular follow - ups may be apprise to note any changes that would take treatment of goitre .
In case of goiter , in which the thyroid hormone stage are either low or high may requirement treatment to adjust the endocrine levels . This can avail to keep struma or thyroid expansion and symptoms of thyromegaly under control . For goiter due to I deficiency , usually atomic number 53 substitute is give .
Thyroidectomy – For some case of thyromegaly , operative treatment option ( thyroidectomy ) may be consider as appropriate . Surgery for goitre depends on the suit and asperity of the condition . operative intervention may involve removing a part or entire thyroid gland secretor in some austere cases . Thyroidectomy may have risk of some complications like damage to a nerve or to the parathyroid secretory organ . It is advisable to seek medical opinion and hash out the skillful possible treatment choice for struma .
In typesetter’s case of thyroid cancer , operative discourse for thyroid gland cancer is consider . extra treatment for thyroid gland cancer may be required , depending on the rigorousness and stage of Crab .
Radioactive Iodine – Another treatment option for struma related to an overactive thyroid gland includes discourse with radioactive iodine . The medication may be given through a drink or a capsule , which is postulate orally . It reaches the thyroid gland and demolish thyroid cells , which are responsible for overrun of hormones . However , there are chances that this handling may result in underproduction of thyroid hormones , which need to be handle with oral medications .
With unlike type of goiter and various handling options for goiter , it is important to search timely medical advice and take after it scrupulously . equal I intake is essential for all , particularly in case of pregnant or wet women and children .
References :
Also Read :