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manly hypogonadism is a condition in which the testes / testicles does not produce adequate amount of testosterone , which is the internal secretion that plays a key office in intimate , cognitive , consistency function and developing . There are two character of male hypogonadism
Primary Male Hypogonadism : This is also call main testicular failure and the trouble is in the testicles .
subaltern Male Hypogonadism : In junior-grade hypogonadism the problem is in the hypothalamus or in the pituitary gland . The hypothalamus produce gonadotropic hormone - releasing hormone ( GnRH ) and it perk up the pituitary gland to produce follicle - stimulating hormone ( follicle-stimulating hormone ) and luteinizing hormone ( LH ) . LH acts on the testes and signals the egg to make testosterone .
What Causes Male Hypogonadism?
Even though the crusade of male hypogonadism are divided into master and secondary , sometimes both can occur at the same sentence .
Causes of Primary Male Hypogonadism
Undescended Testis : Undescended testis can do male hypogonadism . In a male fetus the bollock get in the abdomen and it gradually descend down the inguinal duct to its final position the scrotum . Usually when a male child is born the ball is already in the scrotum . But , sometimes one or both the testicles may not have descend by birth . The testis can descend itself without any intervention within the first year of life . If not it should be surgically placed inside the scrotum . If not decline the testicles role will break and there will not be any testosterone or spermatozoon production .
Klinefelter Syndrome . Klinefelter Syndrome can cause manly hypogonadism . It is a genic condition , an abnormality of the sex chromosomes . Normal chromosomal traffic pattern in a male person is XY . Klinefelter syndrome people have XXY ( additional X ) . The excess X chromosome in Klinefelter syndrome cause abnormal development of the testicles and causetestosterone deficiency .
Mumps Orchitis : Mumpsinfection ordinarily involves the salivary secretory organ . If a male person gets the epidemic parotitis transmission during adolescence or adulthood then there is a chance of getting mumpsorchitis , which can damage the egg and make testosterone deficiency and problems with sperm yield .
Injury To The Testicles : ballock are situate out of doors of the stomach therefore , it is more prostrate to trauma and harm . Injury to testes can do male hypogonadism . scathe to both testicles can cause hypogonadism but , if only one ballock is damaged there will be some less amount of testosterone production .
Hemochromatosis : Hemochromatosisis a term when there is an excessive amount of iron in the descent . Iron can deposit in the testicles and can stimulate manly hypogonadism . It also can lodge in the pituitary gland and make secondary hypogonadism .
Cancer Treatment : Chemotherapyand radiotherapy can step in with the normal testosterone and sperm production and can cause manful hypogonadism . Most of the time these core are irregular , but permanent infertility can occur .
Normal ageing : With geezerhood , the normal testosterone production step by step reduces . Therefore , older men have dilute testosterone levels than younger male person and may grow manful hypogonadism .
Causes of Secondary Male Hypogonadism
Pituitary disorder : job in the pituitary gland block the internal secretion secreted by the pituitary gland and this reduce the yield of testosterone in the bollock induce manly hypogonadism . Pituitary gland tumor , wit tumoradjacent to the pituitary , operative discourse of the pituitary gland can cause damage to the pituitary .
Kallmann Syndrome : inherited condition that causes innate hypogondotrophic hypogonadism due to a trouble in the secretion of GnRH in the hypothalamus . This causes secondary virile hypogonadism .
Inflammatory Diseases : Some instigative condition like histiocytosis , sarcoidosisand tuberculosis can demand the hypothalamus and pituitary secreter and this affect the testosterone production and cause male hypogonadism .
Medications : Opiate painfulness medications and some internal secretion can affect testosterone output .
Obesity . Beingoverweightcan cause manlike hypogonadism at any historic period .
HIV / AIDS . It causes low-pitched testosterone by affecting the hypothalamus , pituitary and testes .
Stress - Induced Hypogonadism : Stress , inordinate forcible activity , underweight all run to male hypogonadism . The exact chemical mechanism is strange ; however , it can be due to surplus cortisol output with nerve-wracking activities and suppressing the hypothamus
Summary
Male hypogonadism is a shape in which the testes / testis does not bring on adequate amount of testosterone , which is the endocrine that plays a primal role in sexual , cognitive , body use and development . There are two types of virile hypogonadism , primary and secondary hypogonadism . In elementary hypogonadism the problem is in the testicles . causa of elemental hypogonadism admit undescended testis , Klinefelter syndrome , wound to the testis , mumps orchitis , hemochromatosis , normal ageing and cancer treatment . In petty hypogonadism the trouble is in the hypothalamus or in the pituitary secretor . Causes for secondary hypogonadism include pituitary disorders , Kallmann syndrome , inflammatory diseases , medications , obesity , HIV / AIDS and focus - induce hypogonadism .
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