Scleroderma is an autoimmune disease . This means that it is a condition that make the consistence ’s immune system assault its own tissue . Scleroderma may change a lot in terms of severity . In some cases , it can be a meek condition , while in others it can be a life sentence - threatening situation .
What Are The First Signs Of Scleroderma?
The most common symptom of scleroderma disease is a hardening or tightening of patches of skin , however , one of the first signaling of scleroderma is an exaggerated reaction to cold temperatures or aroused distress , which can cause apathy , pain or discoloration of the fingers or toes . This experimental condition , also calledRaynaud ’s disease , also occurs in people who do not have scleroderma .
There are two main types of scleroderma : the systemic ( systemic sclerosis , SSc ) , which normally affects the skin and the internal organs or arrangement of the trunk , and the localized scleroderma .
What is Systemic Sclerosis?
There are two main types of systemic induration or SSc , for its acronym in English : the limited cutaneal systemic sclerosis and pervade cutaneous systemic sclerosis . The difference between limited and circularize systemic cutaneous sclerosis lies in the extent of the affected skin . In the special cutaneous systemic induration , the thickening of the skin occurs only in the hands and forearm , human foot and lower part of legs . In direct contrast , pass around cutaneous systemic sclerosis affects the hand , the forearms , the upper arms , the thighs or the trunk . Both mode can impress the face .
Both circumscribed and diffuse dermal systemic sclerosis may have serious clinical characteristics . For example , the phenomenon of Raynaud is presented in both modalities of the disease . The Raynaud phenomenon is a condition which causes the skin of the fingers to bend white or bluish during exposure to cold and then call on red or violet when it regain the warmth . These episodes are triggered by a cramp of the humble blood vessels that are in the finger’s breadth . Over metre , these humble bloodline vessel they suffer legal injury to the period that they can persist whole clogged , this can make them appear ulcerations on the fingertips . The phenomenon of Raynaud is present in almost all patients with systemic sclerosis ( 95 % ) .
Almost all patients with systemic sclerosis also have affected the esophagus , which loses normal movement . In upshot , the food can “ get nonplus ” in the esophagus and the abdomen acid may go up into the oesophagus and induce pyrosis .
Telangiectasias are small reddened Lucy in the sky with diamonds that seem in the hands , arms , face or trunk . They are tiny line vessels of the cutis that have distend .
Patients affected by diffuse cutaneous systemic induration are at increased jeopardy of developing pulmonary fibrosis disease or interstitial lung disease ( mark on the lung tissue that make breathing unmanageable ) , kidney disease and intestinal disease .
Renal involvement pass off and usually manifests as a sudden increment in blood pressing .
The risk of extensive intestine involvement , with slowing of movements or movement of the tummy and intestines origin the follow symptoms : the sensation of swelling after eating , diarrheaor periods ofconstipationalternated with periods of diarrhea .
Calcinosis refers to the comportment of atomic number 20 deposits in the skin or just below it .
pneumonic high blood pressure is in high spirits blood pressure in the blood vessels of the lungs . The most frequent symptom isshortness of breath(difficulty ventilation ) when an crusade is made .
What is Localized Scleroderma?
Morphea manifests as plaques or patch of thickened skin that can be from half an inch to six in in diameter . Some mass only have one or a few plate , while others have several scattered throughout the consistence . The memorial tablet may be lighter or non-white in colour than the wall hide and , therefore , they usually stand out .
Linear genus Scleroderma manifests as a flight strip of thickened skin along with an limb or side of a leg . The subcutaneous layer of fatness can be lose so that the bear on limb is thinner than the one that is not .
Scleroderma in coup de saber is a modality of linear scleroderma , in which the thickened peel origin appears on the os frontale or on another part of the face .
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