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What is Hydroxyapatite?
Hydroxyapatite is an inorganic fabric that is course present in human bones and tooth . It has a role to play in the bone ’s structural forcefulness and osseous tissue positive feedback . doctor use synthetic hydroxyapatite for bone repair discussion .
Hydroxyapatite forge 65 % of the bones and provides rigidity to the bone and teeth.(1)It shape 70 - 80 % of the exercising weight of human dentine and enamel.(3)It is also known to repress occasional heftiness soreness from everyday sweat . It is more readily absorbed than calcium . It can get bear on negatively by high-pitched sugar and acidic beverage . Overall , hydroxyapatite is an significant mineral for bone health as it provides structural strength and reduces muscle discomfort . It is a main part of ivory re-formation and can be modified to improve the bone ’s osteoconductive properties .
Composition of Bone
pearl are complex tissues that consist of several components include cells , extracellular matrix , and mineral . The extracellular intercellular substance is form of the following :
asunder from collagen fibers and hydroxyapatite crystal , ivory also contains several types of cubicle including bone-forming cell ( Bone forming cells ) , osteoclast ( Bone - resorbing cell ) , and osteocytes ( mature bone cell ) .
Bone has a complex composition including both constitutive and inorganic element . There are several case of cells playing the role of maintaining bone health and function .
Function of Hydroxyapatite in Bone
Hydroxyapatite is present in pearl and teeth . Its crystals are present in bone in the shape of plates or needles and may depart in routine , size , and shape .
The functions of hydroxyapatite include :
Hydroxyapatite is also used in osseous tissue grafting procedures in which a small opus of bone is removed from one part of the body and transplanted to another area when the osseous tissue is needed . The role of hydroxyapatite is to rush the growth of new bone .
Formation of Hydroxyapatite in Bone
The geological formation of hydroxyapatite is a complex process and require dissimilar cellular and molecular interaction .
Process of Bone Formation
It begins with the deposition of collagen fibers that make up the constituent component of the bone . These fibers serve as a framework in which the hydroxyapatite crystals grow . Then the calcium and phosphate ion begin compile on the collagen fibers forming small crystal of hydroxyapatite .
Role of Osteoclast , Osteoblast , and Osteocytes
Several type of cadre including osteoclast , osteoblast , and osteocytes are involved in the shaping and care of bone tissue . bone-forming cell synthesize and deposition collagen fiber , and osteocyte regulate the bone remodeling and mineralization and osteoclast breakdown and resorb bone tissue . This process is indispensable for the maintenance of tidy bones . Any disruption in the process can lead to skeletal disorders .
Importance of Vitamin D and Calcium in Hydroxyapatite Formation
Ca allow for structural support to the bones and teeth . Insufficient Ca levels in the blood weaken the bones and increase the risk of fracture . It also helps in asseverate healthy muscle and nerves and regularize many corporeal function .
Vitamin D is also important for the absorption of calcium from the diet and its usage in the body . Together , atomic number 20 and vitamin promote the formation of hydroxyapatite . The want of both can affect the establishment of hydroxyapatite and lead to weakened bones , tooth radioactive decay , and other health job .
Factors Affecting Hydroxyapatite in Bone
There are several factors that may affect the geological formation and upkeep of hydroxyapatite in the bone .
Conclusion
Hydroxyapatite is a crucial component of os tissue , providing bone with strong point and rigidity and the power to withstand mechanical emphasis . It is a complex mineral compose of calcium , phosphorus , and other mineral and forms a dense mineral matrix in osseous tissue tissue paper . It is important for resist compressive forces .
Several factor influence the geological formation of hydroxyapatite including nutrition , hormone , physical activity , age , genetics , and aesculapian conditions . Adequate inspiration of calcium , phosphorus , and other substantive nutrient is necessary for the organization of hydroxyapatite .
Taking whole step to further bone health can help ensure the bones remain strong and healthy throughout biography .