Plateletsare the little parentage cells that play a decisive role in the process of rip clotting . A down platelet enumeration , also known as thrombocytopenia , can be due to a variety of aesculapian conditions . When platelets are too low , there is an increased risk of infection of bleeding or bruising , which can lead to serious health issues .
Understanding the Causes and Symptoms of Low Platelet Count (Thrombocytopenia)
Here are some medical condition that can get a drop in your thrombocyte count :
Immune Thrombocytopenia (ITP)
Immune thrombocytopenia ( ITP ) is a aesculapian status that can have a drop in your blood platelet count . thrombocyte are small cell in your blood that help your blood clot , so a low platelet count can make problems with bleeding and bruising .
ITP is an autoimmune disorder , meaning your body’simmune systemmistakenly attempt and destroy your thrombocyte . The precise cause of ITP is unknown , but it can be trigger off by viral infection , medication , or other medical conditions .
Symptoms of ITP let in easybruising , bleed gum , nosebleeds , and little scarlet or purple spot on your skin called petechiae . In some case , ITP may not cause any symptoms at all . ITP can be diagnosed through line of descent tests and a strong-arm exam . Treatment options for ITP include medications to suppress the immune system and increase platelet yield , as well as blood transfusions in dangerous cases .
If you have a low thrombocyte numeration or any symptoms of ITP , it is important to talk with your health care provider for right diagnosing and discussion .
Viral Infections
Viral infectionsare one of the common causa of a low platelet count , also know asthrombocytopenia . Many different case of viruses can cause thrombocytopenia , includingdengue , Zika , and Epstein - Barr virus .
When a person is infect with a computer virus , their immune system react by bring on antibody to contend the virus . Sometimes , the resistant response can also assault the platelets in the origin , leading to a decrease in platelet count . In some showcase , the computer virus itself can directly taint the bone marrow , where thrombocyte are produce , and cause a decrease in platelet count .
Symptoms of thrombocytopenia cause by a viral contagion can include easy bruising , bleeding gums , epistaxis , and petechiae , which are humble purple or red spots on the hide .
discussion for thrombocytopenia because of a viral infection count on the severity of the condition and the fundamental cause of the virus . In some cases , the blood platelet count may improve on its own once the virus is address or conclude . In other case , medication or other treatments may be postulate to increase the platelet count and keep bleeding complications . It is significant to work closely with a healthcare provider to determine the most appropriate discourse architectural plan for each individual case .
Cancer
genus Cancer can be a cause of gloomy platelet numeration or thrombocytopenia , especially when the malignant neoplastic disease feign the ivory centre , where platelets are create . As cancer cell grow , they can crowd out healthy jail cell in thebone marrow , resulting in a lessen thrombocyte tally .
Some type of cancer that can make humiliated platelet count admit leukemia , lymphoma , andmultiple myeloma . In increase , cancer treatments such as chemotherapy and radiation therapy can also pretend the pearl marrow and conduct to a decreased platelet count .
symptom of low platelet count due to cancer can include promiscuous bruising and bleeding , nosebleeds , and prolong bleeding from cuts or injuries . discussion options for low thrombocyte count cause by cancer may include medicinal drug to stimulate the production of platelets , pedigree transfusion , and in some cases , off-white substance transplant . It is important for genus Cancer affected role to work close with their healthcare squad to manage any symptom and side effects , including low thrombocyte count .
Medications
sealed medication can cause a decrease in thrombocyte enumeration , leading to a experimental condition known as drug - get thrombocytopenia . This condition is typically due to medicament that dissemble platelet production or survival , or trip an immune reaction against thrombocyte . Common medications that can cause thrombocytopenia include chemotherapy drugs , antibiotics , anticonvulsants , and diuretics .
Drug - induced thrombocytopenia can be either soft or severe , depending on the medication and the individual ’s response to it . Symptoms can range from easy bruising and prolonged bleeding to life - threatening hemorrhage . In some cases , drug - have thrombopenia may resolve after the medication is discontinued , while in other guinea pig , intervention may be necessary to restore normal blood platelet counts .
It is important to inform your doctor of any medication you are take and to monitor your thrombocyte count if you are necessitate a medication known to do thrombopenia . If you have symptom of thrombocytopenia , such as unexplained bruising or bleeding , seek medical attention immediately .
Pregnancy
Pregnancy is a complex physiologic appendage that can do changes in many systems of the body , including the blood curdle arrangement . In some cases , maternity can top to a drop in platelet count , a condition know as gestational thrombopenia .
Gestational thrombocytopenia is a mutual circumstance that strike roughly 7 - 8 % of pregnant women . It is by and large mild and resolves on its own after delivery . However , in rare cases , it can lead to more serious knottiness such as run during delivery or the growth of a uncommon but serious condition called pre - eclampsia .
The exact cause of gestational thrombocytopenia is not fully understood , but it is believe to be have-to doe with to change in endocrine levels during pregnancy . In some cases , the condition may be related to an autoimmune response where the female parent ’s resistant arrangement attacks her own thrombocyte .
Women who develop gestational thrombocytopenia will typically have platelet count between 100,000 and 150,000 per microliter of blood . The condition is typically symptomless and is usually discovered during routine origin tests .
If a fraught woman develops thrombocytopenia , her healthcare supplier will supervise her platelet count nearly to ensure it does not drop to dangerous levels . In severe cases , treatment may be necessary to prevent bleeding during delivery . Women with gestational thrombopenia should talk to their healthcare provider about any concerns or questions they may have about their condition and the potential risk or knottiness .
Genetic Disorders
Low thrombocyte count can be cause by genetic disorders such as Wiskott - Aldrich syndrome , May - Hegglin anomaly , and Bernard - Soulier syndrome . These disorders dissemble the factor responsible for the output and procedure of platelets . In Wiskott - Aldrich syndrome , for example , the gene that codes for the protein that helps form the platelet cytoskeleton is mutate . As a result , the platelets are littler , few in turn , and less able to form clots . likewise , in Bernard - Soulier syndrome , there is a defect in the gene that codes for the glycoprotein complex that is important for platelet bond . This results in a lessen ability of platelet to cling to blood vessel bulwark .
People with these genetic upset may have a lifelong humble blood platelet count and may have symptoms such as easygoing bruising , nosebleeds , and excessive hemorrhage after injury or surgery . Treatment may include platelet transfusion , medication that rush the production of platelets , and in knockout cases , bone vegetable marrow or root cell transplants . It is authoritative for individuals with a family history of these genetic disorders to be cognizant of the star sign and symptoms and to seek medical attention if they surmise a low thrombocyte count .
In decision , a low platelet count can be because of a variety of aesculapian conditions , and it is authoritative to distinguish the underlying cause in society to allow appropriate treatment . If you are experiencing symptom of a low thrombocyte counting , such as easy bruise or protracted haemorrhage , confer with with your healthcare provider to determine the cause and the best course of treatment .
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