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Is Microscopic Colitis An Autoimmune Disease?
Microscopic inflammatory bowel disease is an inflammatory disorder of the Aspinwall or your orotund intestine that leads to watery diarrhea & spasm . It is a character of incitive bowel disease , & not an autoimmune disease . It is shout microscopic because the excitation can only be seen under a microscope as it is too small to be visualise with the naked eye . Lymphocytic & collagenous inflammatory bowel disease are 2 form of roll in the hay microscopical colitis . In lymphocytic colitis , the patients present with a growth in lymph cell or wbc cell in the lining of the colon while in collagenous colitis the fibrous fall in tissue below the epithelium becomes concentrated , that is also jazz as the collagen layer .
Causes & Symptoms Of Microscopic Colitis
Microscopic colitis is usually seen in hoi polloi honest-to-god than 50 years of eld , specially those who suffer from a certain autoimmune disease such asrheumatoid arthritis , thyroid diseases , celiac illness & psoriasis . Some medicines that reduce inflammation ( NSAIDs ) like ibuprofen , aspirin & naproxen top to microscopic inflammatory bowel disease . Antacids & heartburn drug , antidepressants & anti - cancer drugs stimulate colitis , while people with heart disease are more prone to microscopic colitis . infection induced by viruses & bacterium lead to fervor in the colon causing inflammatory bowel disease . It is also known to run in families , affect first degree relatives ( patrimonial ) . Chronic smokers are also at a risk of develop microscopical colitis .
Symptoms of Microscopic Colitis Include :
The most coarse symptom isdiarrhea(non - bally ) that run for time being . The person also has increased bowel cause . Other symptoms are consistent loss of weight , nuisance in abdomen ( cramps ) , leaky stools due to increased mobility of gut move ) , dehydration , nausea due to gall Elvis mal - absorption that results in watery stools . Due to edema & ignition of the Aspinwall ’s facing there is less absorption of water from the undigested food , & the excess water system is removed from the eubstance as diarrhea along with pus & fluid & sometimes there can be leech from the liner of the colon due to ulceration , which evidence as rectal haemorrhage .
Diagnosis of Microscopic Colitis
The patient normally consecrate a story of washy looseness of the bowels that is colligate with deprivation of weight , abdominal pain & fatigue without rilievo for more than two weeks . The check of diagnosing is made with the aid of multiple biopsy aim from dissimilar segments of El Salvadoran colon from different regions . This is helpful in wee-wee an accurate diagnosing since one segment of Costa Rican colon might be unnatural while the other can be normal .
microscopical colitis has a patchy statistical distribution due to which flexible sigmoidoscopy is not enough to name the status since freakishness of the disease may be absent from one segment of colon & salute elsewhere . Thus , it is utilitarian to take biopsies of other regions of the colon via colonoscopy to name microscopic colitis .
What Is The Treatment For Microscopic Colitis?
Mostly microscopic colitis goes off on its own without any aesculapian discourse . Your MD might require you to avoid food & drinking that might aggravate your symptoms likecaffeine & dairy product . take fiber supplements is helpful in most cases . In case the symptoms are not controlled then over the counter drugs to control diarrhea ( Imodium & Pepto - Bismol ) can be given . To reduce swelling sulfasalazine such as azulfidine is used or sex hormone are given .
Other drugs used to control colitis are mesalamine , cholecystramine , budenoside , & prednoisone . Immunosuppressive therapy is being used where patient fail to respond to steroids or when there is lapse of the disease . Imuran or 6 - mercaptopurine & methotrexate are the drugs of selection . Surgical interference is call for when no medication provides relief to the patient .
Prognosis Of Microscopic Colitis
The prognosis of microscopic inflammatory bowel disease remains unclear . In some patients ( approx two - thirds ) the diarrhea resolves spontaneously after several years while in others ( one - third ) the status continue uncured . The patient experience unyielding or intermittent diarrhoea along with abdominal pain for many years without any relieve in the symptoms .
However , with some dietary changes ( by avoiding artificial lettuce & caffeine , eating Milk River loose & gluten innocent diet & drinking plenty of liquid ) sure people have shown benefits in the long run .
References :
“ Microscopic Colitis : A Review of Etiology , Treatment and Refractory Disease ” by NCBI Link : https://www.ncbi.nlm.nih.gov / pmc / articles / PMC3567062/
“ Microscopic Colitis : Causes , Symptoms , and Treatment ” by Cleveland Clinic Link : https://my.clevelandclinic.org / wellness / diseases/17729 - microscopic - colitis
“ Microscopic Colitis ” by National Institute of Diabetes and Digestive and Kidney Diseases ( NIDDK ) Link : https://www.niddk.nih.gov / health - information / digestive - diseases / microscopical - colitis
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