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Lichen planus ( LP ) is recurrent chronic autoimmune disease of the skin and mucose tissue layer . It is characterized by minor , shiny , reddened - pinkish lesion that are raised from the normal surface , may flock together and have scaly brass . It ’s seen primarily in the oral enclosed space and skin . It can also fall out in other stead such as the privates , ear , eyes and scalp . It ’s common in the middle aged adults . Women are common to get oral lichen planus double as men .
How Can One Get Lichen Planus?
It ’s a thyroxine - cell liaise auto immune disease , where the T - cells destroy the normal mobile phone of the pelt and mucous membranes remember these cells are pathological . There are several possible cause and risk factor . These gene may make the resistant system think that there are pathological cells and to get free of them by destroying them . However , it ’s indecipherable how these factors shake the resistant organisation to attack the respectable cellular telephone just , but when the below mentioned drug and chemical are barricade and when the disease are treated lichen planus also heal .
It is not aggravated by any food detail ; however , spicy foods , love apple and citrus juices may aggravate the receptive sore in the mouthpiece .
Precipitating ingredient For Lichen Planus :
Viral infections – hepatitis B , hepatitis C
Drugs – There are some drugs that make lichen planus . The mechanics how it really causes the wound is strange . drug given for the treatment ofmalaria , high blood pressure , and anti - inflammatory drugs may make lichen planus . Make certain you tell all the drugs you are train to your doctor if you have lichen planus . Drug induced lichen planus sometimes is identical from the non - drug induced lichen planus . Sometimes the drug induced lichen planus can await like eczema ( another cutis condition ) .
Beta blocker – These are used for treat cardiovascular disease for instance atenolol , propranolol , metaprolol , carvedilol
ACE inhibitor – captopril , enlapril , lisinopril
Thiazide diuretics – Hygroton , hydrochlorothiazide
Antimalarial drug – quinidine , chloroquine ,
Sulfonylureas – tolbutamide , glipizide , glimperide , chlorpropamide
phenothiazine – a tranquilizing drug with antipsychotic properties
Gold – it was used to treat inflammatory conditions likerheumatoid arthritis . Now not used because of the side effects .
Arsenic – not used unremarkably
Penicillamine – It is not usually used now . It was used to treat rheumaticarthritisandWilson ’s disease
NSAIDS – ibuprofen , naproxen
Other factor :
genetic science – a rare var. of lichen planus called genetic bullous lichen planus runs in the families .
tenseness – this is debatable
Vaccines – hepatitis B , influenza vaccinum
Diseases – primary biliary cirrhosis of the liver
Reactions – Lichenoid eruptions come with transplant - versus - host disease ( it ’s a reaction that occur in patient who have received bone marrow implants )
chemical substance - Certain chemical used in the color photograph industriousness
Mercury tooth filling – can cause oral lichen planus
Conclusion
Lichen planus is a repeated chronic autoimmune disease that is assure commonly in in-between cured adults . It ’s seen unremarkably in the unwritten enclosed space , other than that it ’s seen in the tegument , genitals , scalp , ears and eyes . It ’s a T - cadre mediate autoimmune disease where the immune organization ruin the sizable cells in the skin and mucous membranes thinking these cell are pathologic . The accurate cause for this stimulant of the immune scheme is obscure however there several precipitating factor that is identified to trigger lichen planus . Some of these are drugs such as genus Beta blocker , ACE inhibitor , thiazide diuretics , anti - malarial drug and NSAID ’s . Other trigger factors include viral infection like hepatitis B & C , genetics , stress , vaccinum , sure chemical used in the colouring material photography diligence and atomic number 80 tooth fillings .
reference :
DermNet NZ – Lichen Planus Link : https://dermnetnz.org / topics / lichen - planus/
WebMD – Lichen Planus Link : https://www.webmd.com / hide - trouble - and - treatments / lichen - planus
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