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Akidneydisease when causes retention of metabolites , mineral and water results in kidney disfunction . Focal Segmental Glomerulosclerosis ( FSGS ) is one of the kidney disorders that results in multiple symptom . Early symptom are warning sign of the zodiac and should be appraise as presently as possible . time lag in reasoning by elimination of suit of the disease and delay of the treatment can cause irreversible kidney damage . mark or hardening of the vessels of the kidney make the Glomerulosclerosis of the kidney . In this article , we will discourse about the causes , danger broker , symptom , and treatments render for Focal Segmental Glomerulosclerosis ( FSGS ) .
How Is Focal Segmental Glomerulosclerosis (FSGS)?
Focal Segmental Glomerulosclerosis ( FSGS ) is the scarring or hardening of the glomerulus and the ancestry vessels of the kidneys . glomerulus are a shallow funnel shape like stricture , which agree within funnel shape blood line vessels and capillaries . The funnel shape and its tube-shaped structure filter H2O , minerals , and metabolite . Some of the water and minerals are reabsorbed in tube which is attached to funnel . There are several thousands of tiny glomerulus in kidney . The subroutine of the glomeruli is to filtrate the blood and cast aside the metabolites as well as extravagant mineral and water . Thus urine contain unwanted water , metabolites and mineral . Glomerular abnormalities stimulate by scarring and abnormal rip vessels effect in abnormal reabsorption of metabolites that ensue in toxic systemic effects on human consistency . inordinate reabsorption or excretion of water and mineral causes disease of electrolyte abnormalities . In moderate to severe cases glomeruli start lose protein resulting in proteinuria . Focal Segmental Glomerulosclerosis affects both children as well as adults . Gender wise , it is more prevalent in Male than females .
Causes of Focal Segmental Glomerulosclerosis (FSGS)
Idiopathic Primary Focal Glomerulonephritis-
Focal Segmental Glomerulosclerosis generally fall out when cause is unknown . The disease is then bang as Idiopathic or Primary Focal Segmental Glomerulosclerosis .
Known Causes of Focal Segmental Glomerulosclerosis (FSGS) Are:
Symptoms of Focal Segmental Glomerulosclerosis (FSGS)
Initial Stage Symptoms of Focal Segmental Glomerulosclerosis (FSGS):
Later Stage Symptoms of Focal Segmental Glomerulosclerosis (FSGS):
Diagnosis of Focal Segmental Glomerulosclerosis (FSGS)
In order of magnitude to confirm the diagnosis of Focal Segmental Glomerulosclerosis , the physician may do a detailed physical scrutiny , which may place tissue paper swelling and hypertension . The medico may also discover signs that may point renal failure or collection of exuberant fluid in the body . Some of the tests to confirm the diagnosing of Focal Segmental Glomerulosclerosis are :
Urine Examination - Urine scrutiny may show following abnormalities-
Urine Microscopic Examination - Examinations may show following abnormal findings-
Renal Biopsy - Abnormal determination of biopsy include following abnormalities-
Treatment For Focal Segmental Glomerulosclerosis (FSGS)
Unfortunately , there is no clear - cut treatment for Focal Segmental Glomerulosclerosis but there are numerous treatment , which one can slow up down disease progression . The symptom are often less significant with treatment and prognosis suggest discourse does prolong life .
regrettably , Focal Segmental Glomerulosclerosis ( FSGS ) have an eventual nephritic failure even with appropriate treatment . Appropriate handling and follow up prolongs the kidney damage and need for dialysis . In cases where kidney is severely damaged then patient agony with advanced Focal Segmental Glomerulosclerosis need to have dialysis and/or kidney transplant .
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