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Introduction
Background on Fluoride Exposure
Fluoride is a naturally come component that is wide distribute in the environment . It can be found in the dirt , urine source , rock , and various other minerals . It is also known to be present in many solid food items , plants , and even in the breeze we breathe .
The use of fluoride in public wellness gained gibbosity in the early 20th hundred as it was discovered that the community with naturally fluoridated piss had fewer dental cavities . Fluoride since then has been added to water and incorporated in dental products such as toothpaste and mouthwashes , as a preventive measure to cut tooth decay and better unwritten wellness .
It ’s also worth noting that fluoride can lead to small levels of thyroid gland hormones(1 ) . This may cause the pituitary to let go more thyroid internal secretion head to health tortuousness . iodin is responsible for the proper operation of the thyroid gland . Fluoride interpose with the power of I to produce hormones in the thyroid gland secretory organ . The inability of the body to produce enough thyroid gland internal secretion leads tohypothyroidism .
Fluoride exposure depend on geographical fix , water sources , cultural practice , and public wellness policies .
In some industry , the workers may be exposed to high levels of fluoride .
The prevalence of fluoride photo depart globally and may have an encroachment on dental health and other wellness aspects such as pituitary secretory organ function .
Importance of Pituitary Gland in Hormonal Regulation
The pituitary secreter , often referred to as the original gland , regulates various hormonal operation in the body . It is settle at the base of the brain and is small pea - sized and has an immense influence on the endocrine secretor .
The importance of the pituitary gland in hormone regulation includes :
The pituitary gland influences metabolism and energy balance by producing thyroid - stimulating hormone ( TSH ) . It move the thyroid gland to loose Thyroxine ( T4 ) and triiodothyronine ( T3 ) .
Fluoride and Endocrine System
The endocrine gland organization comprises a internet of gland . These glands produce and secrete hormones , act as chemical courier that regulate various physiologic processes in the consistence .
Fluoride impacts two gland in the internal secretion system including the pituitary and pineal secreter . It can produce the following hormone effects :
The effects of fluoride on the ductless gland organization are still evolving and may calculate on various factors including individual susceptibleness and environmental influence .
Effect of Fluoride on Pituitary Gland
Fluoride affects the internal secretion released by the pituitary gland . thyroid gland - stimulate internal secretion is released by the pituitary secretor in response to thyrotropin - relinquish internal secretion ( TRH ) . TSH see to it how much T3 and T4 are expel by the thyroid secretory organ .
Fluoride has been observed to diminish the production of Triiodothyronine ( T3 ) and Thyroxine ( T4 ) . By interfering with iodine ’s function in thyroid gland hormone production , fluoride can potentially put up to the onset of hypothyroidism(1 ) . Individuals show decreased levels of T3 and T4 may experience :
Conversely , another research indicated that photograph to fluoride did not lead to a salary increase in Thyroid induce Hormone ( TSH ) levels(6 ) .
Effect of Fluoride on Pineal Gland
The pineal gland is located at the center of the two halves of the brain . It is a small-scale gland that play a role in farm melatonin .
Melatonin is a endocrine that plays a role in establish nap traffic pattern .
Accumulation of fluoride in the pineal secretory organ can inhibit the product of melatonin .. A study suggest in high spirits exposure to fluoride is associate with modification in sleep patterns in adolescents(7 ) . An increase in people ’s exposure to fluoride drinking water advance the risk of sleep disturbance such as sleep apnea . The teenager in the study report sleep 24 minutes after and have out of bed 26 minute later .
Mitigation and Intervention Strategies
Mitigation and bar strategies for the management of fluoride pic focus on cut or controlling the intake of fluoride to levels that are safe to be used within the recommend road map .
The effective strategies let in :
apply the increasing effects of fluoride on hormones , experts emphasize dependable fluoride consumption . Centers for Disease Control and Prevention recommend people drink body of water with an optimal amount of fluoride(8 ) . Fluoride help in preventing tooth decay and can be safe if used appropriately . A multidisciplinary approach involving wellness sanction , environmental agencies , dental professionals , researchers , and the world is crucial for the in effect palliation and prevention of excessive fluoride exposure .
Conclusion
While fluoride offers undeniable benefits for dental health , its broader implications on overall human health , in particular on the ductless gland and pituitary systems , are coming to the stem as a originate arena of concern . To amply comprehend the nuances of fluoride ’s influence on the pituitary gland , further research is imperative . It ’s of the essence to strike a equalizer , insure individuals glean fluoride ’s oral health advantages without jeopardizing the integrity of their endocrine system , particularly the pituitary gland .
