This clause on Epainassist.com has been reexamine by a medical professional person , as well as checked for fact , to assure the reader the intimately possible accuracy .

We travel along a strict editorial policy and we have a zero - tolerance policy regarding any story of piracy . Our articles are resourced from reputable online pages . This article may contains scientific references . The number in the parentheses ( 1 , 2 , 3 ) are clickable links to peer - reviewed scientific papers .

The feedback data link “ Was this Article Helpful ” on this page can be used to describe substance that is not accurate , up - to - date or questionable in any manner .

This clause does not provide medical advice .

What is Serrapeptase?

Serrapeptase is a proteolytic enzyme obtained from the bacteria Serratia marcescens which is present in the enteral area of silkworms . This proteolytic enzyme exchange protein into its smaller poor boy - unitamino acids.[6]It is also known as serratiopeptidase and it possesses anti - incendiary , anodyne , atherosclerotic , and fibrinolytic properties . Due to this , it is used in a variety of consideration such asarthritis , trauma , surgery , odontology , andcarpal tunnel syndrome . It also prevents sum stroke in patient with a thrombus or clot inside the artery due to its fibrinolytic property that lyses the clot and improves blood circulation.[7 ]

Historical Background of Serrapeptase:

Serrapeptase was first studied In Japan for its anti - instigative properties , and it was first used parenterally but now its oral formulation is very vulgar in use . It came on the market in the 1960s and showed very good results in the treatment of rubor . It was commercialize under the brand name Danzen . However , there are other various enzymatic preparations uncommitted to treat inflammation such as parenteral trypsin and chymotrypsin . But enquiry conducted in Europe and Japan in the 1980s and 1990s concluded that serrapeptase was the best enzymatic preparation for the treatment of inflammation.[6 ]

Side Effects Associated With Serrapeptase:

In the United States , serrapeptase is not used as a medicinal drug , or else its phthisis is mostly as a dietary supplement . Since there are no proper regulations for dietary supplements , it is not approve by FDA , that ’s why their side effects and drug interactions are not describe oftentimes . However , it is used all over the worldly concern , so people have set forth reporting some side effects and drug interactions of serratiopeptidase.[3 ]

Minor Side Effects : Research to engagement show that there are more often than not no such side effects tie in with it and not everyone who take this medication can experience the side effects . The minor side effects that are associated with it arejoint annoyance , muscleman soreness , nauseaandstomach nuisance , skin response , coughing , erythema , increase risk of exposure of pneumonia , and increased endangerment of some infections such as bladder infection . Typically , this type of side effect goes off or subsides once we stop using serratiopeptidase.[4 ]

Severe Side result : The stark side effect are mostly rare and seen only in a small fraction of people . The severe side effect which is associated with it is Stevens - Johnson syndrome ( it is a severe skin disease that is characterise by large blisters and even sometimes shedding skin ) . Also in some cases , mass have developed pneumonitis ( a lung inflammation ) which is very rare but also very dangerous if rest untreated.[5]Blood curdling abnormalities are also consort with the usance of serratiopeptidase but chance are very few .

A report bring out in 2016 concluded that serratiopeptidase in some instance may cause an increase in the size of it of an abscess ( a swelling on or inside the body , containing a thick-skulled yellow liquidness which is known as pus ) , in part by split up down masse of cells in neighbour tissue . However , this is only reported in one case and no other clinical signification was know till now.[5 ]

There are no pregnant clinical report usable that determined its safety machine visibility and evaluate its side personal effects . To preclude its side effects , one must have to take this readying under the supervision of a medical practitioner to eliminate the possibility of drug interaction that can happen during medication intake .

Interactions:

As we know serratiopeptidase is used as a supplementation and supplements can interact with other supplements , nutrient , and medicament , many inquiry has suggested that serrapeptase can show drug interaction with certain sort of medications.[6 ]

masses who are on blood thinner medications such as aspirin , clopidogrel , and Coumadin should avoid the use of serratiopeptidase because take this with blood thinner medications can result in wicked bleeding and bruising .

Other supplements such asgarlic , fish oil , andturmericmay also potentiate the risk of bruising and bleeding.[5]Therefore , the use of these accessory in conjugation with serratiopeptidase shall be deflect .

Caution:

As we know any medicine or supplementation is never completely safe for anyone , however , Serrapeptase is look at dependable in equivalence . In some cases , serrapeptase may demand to be avoid to prevent its side effects . However , in clinical trials that are usually short - term , it was determined to be fairly safe and involve only few side effect that involved complications for the patient ’s primary medical condition . Clinical study have not evaluated the rubber of serrapeptase for longsighted - terminus enjoyment , so people with long - term inflammatory disorders should avoid taking this as a medication or take it under the supervision of a medical practitioner.[5 ]

Conditions in which affected role need to take precaution while using serratiopeptidase-

Conclusion:

Serratiopeptidase is a proteolytic enzyme that is used for a variety of stipulation such as in case of thrombus formation inside the artery , treating scar tissue . It also show anti - instigative and anodyne dimension which are used to reduce inflammation as well as pain . There are some types of pocket-size side core linked with its enjoyment such as coughing , joint painfulness , nausea , and venter trouble . As there is no clinical research that shows its safety profile for pregnant and nurse mother , so it is better to avoid this during maternity and breastfeeding . It is also contraindicated in patients with GIT ulcer or any liver disease , and it is recommended that it should be taken only under the supervision of a medical practician to avoid drug interaction and side effects associated with it .

References :

Also Read :