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Narcolepsy is a sleep disorder . The exact movement of this disease is yet to be known . It is a very rarified disease . The main complaint is that there is extreme sleepiness in the daytime in this disease . The affected role also complains of difficulty fall eternal sleep at night . Such multitude find it unmanageable to cope with day-by-day activity . They determine it unmanageable to focalise in schooltime , at home base , at study , and at societal events or gather because they suffer from tiredness due to unconventional quietus at dark . There is no cure for narcolepsy , but few life-style change and medication can make it easygoing to reduce the symptoms.(1 )
Does Narcolepsy Make It Hard To Wake Up?
Narcolepsy is a continuing consideration that principally interferes with the ability of the brain to control the sleep and waken cycle . The main symptom of such patients is extreme daytime sleepiness . The patient does not have a problem in fire up up but has a job to ride out awake throughout the day . During the night also , the patient has hassle staying at rest and wakes up a lot of time in the middle of the night . In the daylight , the patient may fall gone unknowingly while work or driving or talking or eat .
Along withdaytime sleepiness , the patient role also experience loss of muscle shade on the spur of the moment and this leads to a intuitive feeling of weakness and the mortal is unable to practice muscles voluntarily . This is calledcataplexy . Cataplexy is sometimes triggered by certain strong emotion like wrath , strain , fear , laughter , etc . Cataplexy may take weeks or even years to show up after narcolepsy is diagnosed . The frequency of occurrence of cataplexy attacks is not stagnant . Some people might experience two to three attacks in their life-time while others might experience many attacks of cataplexy in one exclusive day . Cataplexy attack pass in sealed muscles only but not in all muscles . The attack lasts for some time and it is unremarkably mild in nature . In cataplexy , the patient does not fall behind consciousness , while in other disorders like convulsions , capture disorders , etc . the affected role loses knowingness . This is the differentiating feature between cataplexy and other seizure disorders . The attacks of cataplexy are not very harmful as they go aside instantaneously on their own after lasting for a few minute of arc . The attack may be mild and may induce very pocket-size symptoms like drooping of eyelid are a few proceedings .
Sometimes the attack may be stark and the affected role may not be able to move his / her soundbox or do any function for a few minute . When this happens the patient can not talk , move or even open heart . But the patient role hold back consciousness during this attack.(2 )
Pathophysiology Of Narcolepsy
Hypocretin , which is also have intercourse as orexin , is a neuropeptide that functions in the mastermind . Neuropeptides are pocket-sized protein - like speck that are used by neurons to communicate amongst each other . This neuropeptide hypocretin works for the regulation of watchfulness . There are more than gazillion of cells in the brainiac but amongst them only around ten to twenty thousand neurons are able to release hypocretin . When there is loss or deficiency of these neuron that produce hypocretin , it result in narcolepsy . It has been found that people with narcolepsy have less number of these hypocretin - producing neuron in their mentality . In narcolepsy , the patient goes into REM sleep straight out after being awake and there might be petty non - REM sleep in between . In the rapid eye movement sleep sleep , the skeletal muscles go into entire atonia due to hyperpolarization of alpha motor nerve cell in the spinal electric cord and brainstem . It has been seen that acetylcholine ( a neurotransmitter ) has been involved in this pathway to cause atonia of muscle . The reason why these hypocretin - producing neurons die is not know yet but some studies evoke it may be due to abnormalcy in the resistant system . It has also been catch that narcolepsy occurs in a seasonal pattern too . It is ascertain more in the summer and spring seasons because these are the season when people get unhinged the most.(2 ) , ( 3 )
Conclusion
Narcolepsy does not make it hard to wake up but the patient faces more problems after arouse up because of daytime somnolence . The affected role feels very sleepyheaded throughout the day and may also suffer from quietus attacks where the patient falls asleep involuntarily anytime and anywhere . The only problem while getting up is that the patient role may brook from slumber palsy and may be ineffective to move for a few minutes after waking up .
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