Mononucleosis is the condition caused due to the contagion of the Epstein Barr computer virus . The condition is more marked in patient with a compromised immune system . The recurrence of the disease did rare but found in patients with the scummy immune system .
Does Mono Weaken Your Immune System?
Various strategies have been evolved by Epstein Barr virus to evade the immune system and take control of the Bel cells . Generally , in case of any infection due to virus or bacteria , the resistant system becomes fighting to fight against the encroacher . This is particularly done by the B cell which pioneer the production of antibody . These antibodies then fight against the infection and vote out the virus or bacteria .
However , in the case of mononucleosis , the computer virus itself invades the group B cells and engage control of the social function . It also constitute a latent contagion in these B cells . This may also lead to an dissymmetry between the computer virus shift and the immune system that leads to the exploitation of various lymphoproliferative disorders . This is done by changing the written text element of the genome responsible for for hold in the functions performed by B cells . These written text component are alter by EBNA2 transcription ingredient from EBV . A study also designate that the attachment of EBNA2 to various portion of the genetic code results in the ontogenesis of disease which is very unrelated . For instance , when EBNA2 seize to one component of genetic code , the risk of developing lymphoma increases and when EBNA2 tie to another dowry of transmitted code , the risk ofmultiple sclerosisincreases .
The Epstein Barr infection affects the off-white center and triggers the development of a big number of lymphocytes . This large percolation of lymphocytes may lead to splenomegaly . Further , the mononucleosis also weakens the resistant system thereby boil down the capacity for push against infection .
It has also been seen that kissing disease increases the incidences of autoimmune diseases such as systemic lupus erythematosus . Once the symptoms of the viral transmission subside and the virus goes in the hibernating level , certain precondition in which patient role is immunocompromised guide the infection to recur . These conditions are pregnancy , electronic organ transplantation , andHIVinfection .
Treatment Of Mono
anodyne . The symptoms of mono colligate to painfulness let in swollen tonsils and swollen lymph node . The patient also suffered from a tender throat . Thus , various analgesics such as ibuprofen and acetylsalicylic acid may be given to the patient . However , care should be taken while lot aspirin to the patient role with thrombocytopenia as complication as aspirin may increase the jeopardy of bleeding .
Antipyretics . As the consistence is oppose against the transmission of the Epstein Barr virus , the temperature of the organic structure is increased . Sometimes the patient experiences a very in high spirits fever . Paracetamol is administered in such patients .
Steroids . Steroids are the drug used to reduce the inflammation . Steroids are used in the patient role which have the symptoms of mononucleosis complications . These symptoms admit acute anemia , thrombocytopenia , CNS disorderliness , and respiratory obstruction .
Antibiotics . Antibiotics are the drugs generally used in viral infection . However , this drug does not crop in viral infection . Sometimes antibiotic are prescribed by the physician to cut the risk of opportunistic bacterial infection for an instance sore throat is make due to streptococcus infection .
Antiviral Drugs . No antiviral drugs are efficacious in the treatment of infection get by Epstein Barr virus . Acyclovir and ganciclovir may reduce the desquamation of virus in the saliva , but they are not effective in complete elimination of computer virus from the body .
Healthy Diet . Diet is also an important scheme for the direction of kissing disease and its return . Vitamin degree centigrade rich foods should be incorporated into the diet .
Conclusion
Epstein Barr computer virus directly invades the B cellphone of the resistant system and controls their function through changes in the transcription gene . Mononucleosis weaken the immune system .
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