This article on Epainassist.com has been critique by a medical master , as well as learn for fact , to assure the readers the advantageously possible accuracy .
We be a rigid editorial policy and we have a zero - tolerance policy regarding any level of plagiarization . Our articles are resourced from reputable on-line pages . This article may contains scientific reference . The numbers game in the parentheses ( 1 , 2 , 3 ) are clickable connection to peer - reexamine scientific papers .
The feedback linkup “ Was this clause Helpful ” on this page can be used to report content that is not accurate , up - to - date or confutable in any fashion .
This clause does not provide medical advice .
Introduction
Colorectal Cancer and Its prevalence
Colorectal cancer also known as bowel or Aspinwall cancer refers to a malignancy that grow in the colon or rectum . It is known to develop from abnormal growths called polypus in the liner of the Costa Rican colon or rectum . Colorectal cancer is the most unwashed type of genus Cancer worldwide and is the most commonly diagnosed cancer in both men and cleaning woman . According to the World Health Organization , it is judge that 1.93 million young shell of colorectal cancer and 10 million deaths take place globally in 2020.(1)Also , high death rate rates are observed in the develop country .
Colorectal cancer regard individuals of all ethnicity and ages and a legal age of case are diagnose in individuals over the eld of 50 years . Also , having a syndicate history of colorectal cancer , incitive bowel disease can further increase the risk of develop the disease .
Importance of Early Detection of Colorectal Cancer
other detection act as an important role in the prospect and natural selection rate of colorectal cancer . If diagnosed at an former stage , the chance of successful intervention and cure are high . Regular screening can be helpful in detect precancerous polyps or former level of cancers . This can further avail in enabling timely interposition and reducing the endangerment of advanced disease .
Overview of Cologuard
What is Cologuard and its Purpose
Cologuard is a non - invasive cover test that can help detect colorectal cancer and precancerous polyps.(2)It is a combination of deoxyribonucleic acid psychoanalysis and faecal immunochemical testing ( FIT ) to analyze a patient ’s can sample for the presence of sure biomarkers associate with colorectal cancer .
The intent of Cologuard is to provide alternate screening choice for people with an average hazard of colorectal malignant neoplastic disease . It is issued for early sensing and bar by identify unnatural DNA and blood biomarkers in the stool that may indicate the bearing of colorectal cancer or precancerous polyp .
How Cologuard Works as a Non-Invasive Screening Test
Cologuard is a non - incursive option to other showing methods likecolonoscopy . It utilize a multitargeted approach to dissect DNA from cellphone shed in the stool.(3)It leave an alternative for colorectal cancer screening that is more convenient and less invasive .
A Cologuard run outfit is provided to the affected role , by a healthcare provider or through a lineal consumer poser . The sample is collected by the patient at home using a provider collection container and following the instructions provide . The sample is packaged and send back to the science lab for analysis .
The sample is test for deoxyribonucleic acid mutation and alterations associated with colorectal genus Cancer . The sample is also tested for the presence of blood in the stool which can be an indication of colorectal Crab orgastrointestinal issues .
A report is generated by the laboratory point whether the test is positive or negative . A positive trial run point a higher likelihood of colorectal cancer or precancerous polyps . However , it should be note that a positively charged psychometric test does not indicate the bearing of colorectal cancer or polyps . Further diagnostic evaluation through colonoscopy is recommend to confirm the determination and take appropriate discourse decisions .
Who Can Go Ahead with Cologuard Procedure
The Cologuard masking mental testing is suitable for grownup who are at an medium risk of the disease . According to the American Cancer Society , a person who is at an average risk of develop colorectal Crab should begin screen at the eld of 45 years.(2)The covering should go on until 75 year of long time . After this , the need for screening should reckon on the person ’s wellness , preference , and life expectancy .
However , Cologuard does not interchange the diagnostic colonoscopy nor does it exchange a surveillance colonoscopy in those at high risk of develop colorectal cancer.(4 )
Advantages and Limitations of Cologuard Compared to Other Screening Methods
Cologuard is a non - invading screening method acting and as compare to other traditional screening methods offers several advantages .
Cologuard bear a miserable danger of complication compared to colonoscopy .
The limitations of Cologuard include :
Before go ahead with Cologuard screening it is crucial to discuss the advantage and limitation with a health care professional .
Advances and Ongoing Research in Improving Cologuard Accuracy
Advances and on-going inquiry are being direct to meliorate the accuracy of Cologuard as a screening test for colorectal Cancer the Crab . Some of the key sphere of focusing in advances for Cologuard include :
on-going advances aim to refine Cologuard ’s truth , raise its sensitiveness and specificity and improve its overall carrying into action as a non - invasive showing test for colorectal cancer .
Conclusion
Cologuard plays a significant role in the detection of colorectal cancer in the high - risk population . It offers a non - trespassing screening option and addresses the challenge and limitations associated with traditional screening method acting .
The future lie in polish the biomarkers used , enhancing DNA depth psychology techniques , and better ancestry - ground biomarker detection .
Cologuard service as a worthful tool in the early detection of colorectal cancer and provide accessibility and compliance , in particular in the gamey - risk population . It has the potency to further improve accuracy , contributing to a unspoilt event and being helpful in reducing the death rate rates in the fight against colorectal cancer .
Also Read :
