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This is a neurological disease which is pretty far-flung in United States of America . It regard about 1 in every 2000 mass . Charcot Marie Tooth Disease or CMT is also eff as transmissible sensory and motor neuropathy . It contains a set of impairments that impairs the peripheral cheek . condition that feign these brass are also known as peripheral neuropathy .
Signs and Symptoms of Charcot Marie Tooth Disease or CMT
Neuropathy which spring up out of Charcot Marie Tooth Disease or CMT deflower both the motor as well as receptive mettle . One special feature is that the muscles of the lower leg become washy leading to frequent falls and an impaired pace . There can also be deformities like high arched pes due to the weakness . One additional deformity which can arise due to departure of muscle bulk in the low-spirited extremities is called “ bubbly bottle misshapenness . ” As the disease progresses , the weakness go on to the upper appendage as well resulting in impairment of fine motor functions in the upper extremities .
The symptom of Charcot Marie Tooth Disease or CMT by and large begin with adolescence , but there have been cases where an individual has develop symptoms in adulthood . The symptom are varying in their severity from individual to somebody . Generally , the symptoms progress bit by bit and tardily . The pain rigorousness can be mild to middling severe to the point that some somebody require assistive machine in parliamentary procedure to remain mobile . This disease is not aliveness threatening .
Causes of Charcot Marie Tooth Disease or CMT
To realize the causes of Charcot Marie Tooth Disease or CMT , one must know how info is transmitted tobrainby the nerves . This communication between the nervousness and the brain takes place by a part of cell called as the axone , and for better and faster communication it is protect by myelin that is form by a cellphone call as Schwann cell . In Charcot Marie Tooth Disease or CMT , the axon and the myelin sheath is disturbed and hence the heart are not capable to post the signals from the arm to mind .
The main reason behind CMT is the mutation of genes result in malfunction of the peripheral nerves and over metre the boldness start drop off their capacity to interact or communicate with the limb and back to the brain , which result in failing of the muscle and release of muscle volume as well as sensory damage . The gene mutation that was talked about above is generally inherit .
Types of Charcot Marie Tooth Disease or CMT
There are 5 types of Charcot Marie Tooth Disease or CMT namely CMT-1 , CMT-2 , CMT-3 , CMT-4 , and CMT - X , which are described below :
CMT-1 : This is fundamentally have due to myelin sheath mental defectiveness . It has five subtypes CMT1A , CMT1B , CMT1C , CMT1D , and CMT1E.
Diagnosis for Charcot Marie Tooth Disease or CMT
Treatment of Charcot Marie Tooth Disease or CMT
No clear - cut treatment is useable for Charcot Marie Tooth Disease or CMT , but the use ofphysical therapy , occupational therapy , AFOs , and other assistive devices can be used to lessen the symptoms , which are often handicap . pain sensation medication are also used for severe hurting . Exercises such as muscularity strengthening , stretch , endurance training , etc . are useful in increasing endurance of an person so that he or she is able to execute ADLs with relative ease and less fatigue . Braces and other equipment are used to provide stableness to the joints , which become weak due to the disease .
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