CFHR5 Nephropathy or Troodos Nephropathy- This pathological status of the kidney is a genetic disorder as a result of variation in gene CFHR5 in which there is comportment of hematuria . This disease is prevailing in Cyprus and till date has not been constitute out of Cyprus . In this clause , we will discuss in detail the clinical presentation , diagnosing , causes , and treatment for CFHR5 Nephropathy or Troodos Nephropathy .
How Is CFHR5 Nephropathy or Troodos Nephropathy Defined?
CFHR5 Nephropathy , which is also know by the name of Troodos Nephropathy is an inherited kidney dysfunction , which till date has only been regain in Cyprus . This disease is cause as a event of genetic mutation in gene CFHR5 . As of today , this disease has not been find in individuals of any filiation other than Cypriots .
What Is The Function Of CFHR5 Gene?
The CFHR5 gene take on a lively role in regulation of a branch of congenital immune system known as substitute complement pathway .
Causes of CFHR5 Nephropathy or Troodos Nephropathy
The major cause of CFHR5 Nephropathy or Troodos Nephropathy is the mutation in gene CFHR5 .
Symptoms of CFHR5 Nephropathy or Troodos Nephropathy
The major symptom of CFHR5 Nephropathy or Troodos Nephropathy is the presence of microscopic amount of bloodline in piss , which can easy be observed on routine urine Dipstick . In some instances , there can be hematuria as well ordinarily in connection with some form ofinfection , which is believed to be due to foreplay of immune system resulting in kidney damage .
Diagnosis of CFHR5 Nephropathy or Troodos Nephropathy
The diagnosing of CFHR5 Nephropathy or Troodos Nephropathy can be support on blood sample and by doing genetic tests . Renal biopsy can also be done for confirmatory diagnosing of CFHR5 Nephropathy or Troodos Nephropathy . The biopsy will typically show dethronement of full complement C3 in the kidney without the presence of immunoglobulins .
Treatment CFHR5 Nephropathy or Troodos Nephropathy
A clear slice handling for CFHR5 Nephropathy or Troodos Nephropathy is still a field of on-going inquiry so as to foreclose nephritic failure from grow in mortal with CFHR5 Nephropathy .
Prognosis of CFHR5 Nephropathy or Troodos Nephropathy
Over time touch on soul tend to develop renal failure requiring dialysis or kidney transplant . For some unsung reasons , only males tend to spring up renal bankruptcy and females even after have hematuria do not develop nephritic nonstarter . In some instance , this disease is known to fall out even after a kidney transplantation , but usually after organ transplant the affected individual tends to have a normal life .
